Due to technical difficulties in printing the label-leaflet format, please find the relevant text below. Text is representative of the leaflet portion of label-leaflet spec no 50414965.
Dispersible Co-codaprin 8/400mg tablets
(codeine phosphate and aspirin)
Read all of this leaflet carefully before you start taking this medicine.
- Keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
Index
1. What Dispersible Co-codaprin tablets are and what they are used for
2. Before you take
3. How to take
4. Possible side effects
5. How to store
6. Further information
What Co-codaprin tablets are and what they are used for
Dispersible Co-codaprin tablets belong to a group of medicines which have analgesic (pain relief), anti-inflammatory (reduce inflammation) and anti-pyretic (reduce temperature) properties.
These tablets may be used for the relief of:
- headache, toothache, migraine, neuralgia (nerve pain), sore throat or period pains.
- symptoms of influenza, feverishness, rheumatic pains, sciatica (nerve pain of the leg/back), lumbago (lower back pain), fibrositis (muscular rheumatism), muscular aches and pains.
Before you take
Do not take Dispersible Co-codaprin tablets and tell your doctor if you have:
an allergy (hypersensitivity) to aspirin, codeine, other opioids, salicylates or non-steroidal anti-inflammatory drugs (NSAIDs) or other ingredients in the product. You may have developed difficulty breathing, a runny nose, itchy skin or swelling after taking aspirin or a NSAID previously (see section 6)- a stomach ulcer or a history of ulcers or indigestion
diarrhoea caused by poisoning or severe bloody diarrhoea (pseudomembranous colitis)
difficulty breathing, or other chronic lung disease
nasal polyps associated with asthma or are having an asthma attack.
haemophilia or other blood clotting disorder or are taking medicines to thin the blood.
Important warning:
There is a possible association between aspirin and Reye’s Syndrome when given to children. Reye’s syndrome is a very rare disease, which can be fatal. For this reason aspirin should not be given to children aged under 16 years, unless on the advice of a doctor.
Check with your doctor or pharmacist before taking Dispersible Co-codaprin tablets if you have:
asthma or allergies
heart, liver or kidney problems or gout- diseased adrenal glands (Addison’s disease) or high blood pressure caused by a tumour near a kidney (phaeochromocytoma)
inflammatory bowel disease
gall bladder disease or gall stones- recently had surgery on your gastro-intestinal tract or urinary system
- an enlarged prostate gland
epilepsy or suffered head injury or raised pressure in the skull (may cause painful eyes, changes in vision or headache behind the eyes)- an underactive or overactive thyroid gland
- muscle weakness (myasthenia gravis)
low blood pressure, are dehydrated or are in shock- suffered from alcoholism, drug abuse or dependence or mental illness
anaemia or suffer from a deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD) this can cause episodes of anaemia after eating certain foods such as fava beans (favism)- systemic lupus erythematosus (SLE) or other connective tissue disease.
Other important warnings:
- do not take for longer than directed by your prescriber
- taking codeine regularly for a long time can lead to addiction, which might cause you to feel restless and irritable when you stop the tablets
- taking a painkiller for headaches too often or for too long can make them worse.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Especially:
- ciprofloxacin (antibacterial medicine)
- Monoamine Oxidase Inhibitors (MAOIs, e.g. moclobemide) to treat depression
- medicines to prevent blood clotting such as warfarin, dipyridamole and heparin
- cyclizine, metoclopramide or domperidone (to prevent sickness)
- guanethidine or diuretics (“water tablets”) e.g. spironolactone, furosemide, acetazolamide (to treat high blood pressure)
- mexiletine (to treat irregular heartbeats)
- loperamide or kaolin (to treat diarrhoea)
- selegiline (for Parkinson’s disease)
- phenytoin or sodium valproate (to treat epilepsy)
- cimetidine (to treat stomach ulcers)
- atropine or hyoscine (to reduce stomach muscle spasm)
- cisapride (to treat gastro-oesophageal reflux disease)
- medicines which affect the nervous system such as sleeping tablets, diazepam and hydroxyzine (for anxiety), amitriptyline (for depression) and medicines to treat mental illness
- muscle relaxants
- buprenorphine and naltrexone (to treat drug addiction) or naloxone (for breathing problems caused by opioids)
- medicines which make your urine more alkaline such as antacids, citrates
- probenecid, sulfinpyrazone (to treat gout)
- methotrexate (to treat some cancers, psoriasis and rheumatic disease)
- antidiabetics
- corticosteroids (to suppress the immune system)
- mifepristone (to induce abortion)
- other non-steroidal anti-inflammatory drugs - NSAIDs for pain and inflammation (eg ibuprofen or naproxen)
- medicines which can cause hearing problems (vancomycin).
Pregnancy and breast-feeding
Avoid taking Dispersible Co-codaprin tablets during pregnancy especially in the last 3 months of pregnancy, during labour or whilst breast-feeding. Ask your doctor or pharmacist for advice before taking this medicine.
Driving and using machines
Dispersible Co-codaprin tablets may cause dizziness, blurred vision or the inability to think clearly.
Make sure you are not affected before you drive or operate machinery.
Surgery and tests
If you need to have an operation including having your teeth removed or blood and urine tests, tell your doctor or dentist you are taking this medicine.
How to take
Always take Dispersible Co-codaprin tablets exactly as your doctor has told you. If you are not sure, check with your doctor or pharmacist.
Avoid alcohol whilst taking this medicine.
After meals, disperse the tablet(s) in a glass of water and drink.
Doses:
Adults, including the elderly
: 1 or 2 tablets every 4 hours as required. No more than 8 tablets in any 24 hour period.
Children under 16 years old
: Not recommended.
If you take more than you should
If you (or someone else) swallow a lot of tablets at the same time, or you think a child may have swallowed any contact your nearest hospital casualty department or tell your doctor immediately.
Symptoms of an overdose include ringing in the ears, a spinning sensation, fast or slow breathing rate, coma, fever, heart or kidney failure, clammy skin, fits, confusion, drowsiness, tiredness, low blood pressure, pinpoint pupils, slow heart beat.
If you forget to take the tablets
Do not take a double dose to make up for a forgotten dose. If you forget to take a dose take it as soon as you remember it and then take the next dose at the right time. Do not take more than one dose in any 4 hour period.
If you stop taking the tablets
If you stop taking the tablets you may develop tremor, difficulty sleeping, feeling or being sick, sweating and increased heart or breathing rate or blood pressure. Talk to your doctor before you stop taking the tablets and follow their advice.
Possible side effects
Like all medicines, Dispersible Co-codaprin tablets can cause side effects, although not everybody gets them. Please tell your doctor or pharmacist if you notice any of the following effects or any effects not listed.
Stop taking Dispersible Co-codaprin and contact your doctor at once if you experience the following signs of an allergic reaction: runny nose, itchy skin, swelling of the face, lips, throat or tongue, worsening of asthma, increased sweating, redness or flushed face.
Tell your doctor if you notice any of the following side effects or notice any other effects not listed:
Gastrointestinal system - stomach ulcers or bleeding which can be severe (you may develop bloody or black tarry stools, severe stomach pain and vomit blood), stomach irritation (mild stomach pain, heartburn and feeling sick), constipation, feeling or being sick, loss of appetite, dry mouth, difficulty in the passage of food through the guts, abdominal pain (may be caused by spasm of the bile ducts) and inflammation of the liver.
Heart - slow heart rate, palpitations, low blood pressure.
Blood - anaemia, changes in numbers and types of blood cells. If you have an increase in number of nose bleeds or notice that you bruise more easily or have more infections talk to your doctor.
Urinary system - difficulty urinating, low abdominal pain (may be caused by spasm of the urinary system)
Ears and eyes - ringing or buzzing in the ear, blurred or double vision, narrowing of the pupil.
Nervous system - confusion, drowsiness, spinning sensation, dizziness, mood changes, hallucinations, restlessness, excitation, fits, headache, difficulty sleeping, nightmares, mental dullness, increased pressure in the skull (painful eyes, changes in vision or headache behind the eyes), tolerance (medicine has less effect) or dependence (suffer from withdrawal symptoms eg tremor, sweating, increased heart rate, increased breathing rate, raised blood pressure and feeling or being sick if the medicine is stopped too quickly).
Other effects - trembling, unusual tiredness or weakness, malaise, low body temperature.
Salicylism - if you take large doses for a long time you may develop symptoms of salicylism, these include: dizziness, ringing or buzzing in the ear, deafness, sweating, feeling or being sick, headache and confusion.
If you are concerned about any side-effects or have any other unusual effects, tell your doctor immediately and seek advice.
How to store
Keep out of the reach and sight of children.
Keep the tablets in a cool dry place, protected from light, tightly stoppered.
Do not use Dispersible Co-codaprin tablets after the expiry date stated on the label/carton/bottle. The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
Further information
What Dispersible Co-codaprin tablets contain
- The active substances (the ingredients that makes the tablets work) are 8mg of codeine phosphate and 400mg aspirin (also known as acetylsalicylic acid).
- The other ingredients are calcium carbonate, cetrimide, maize starch, saccharin sodium, silica, citric acid (E330).
What Dispersible Co-codaprin tablets look like and contents of the pack
Dispersible Co-codaprin are white uncoated tablets.
Pack sizes are 100 tablets.
Marketing Authorisation Holder and manufacturer
This leaflet was last revised in May 2010
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